Editorial mission
Peptide Biologix is a free, open technical reference database for therapeutic and research peptides. The database is intended for working chemists, formulators, analytical scientists, and graduate students who need quick access to canonical molecular data — sequences, molecular formulas, molecular weights, CAS registry numbers, and links to primary literature — without the editorial framing typical of vendor catalogs.
Compiler
This database is compiled and maintained by Dr. Marius Kohler, an independent peptide chemist working out of an unaffiliated chemistry consultancy. Dr. Kohler holds a Ph.D. in Bioorganic Chemistry with a thesis focused on solid-phase peptide synthesis of difficult sequences (β-turn-rich and proline-dense peptides). He has spent roughly fifteen years working with academic and small-pharma synthesis groups, primarily on analytical method development (RP-HPLC, LC-MS, CD spectroscopy, NMR) for peptide characterization.
The database is a personal long-running reference project, not an institutional publication. It exists because no single open reference covers the long tail of research peptides described in this database with consistent formatting, and because formularies are often locked behind vendor login walls.
Scope of coverage
This database currently covers 36 peptides spanning seven chemical classes:
- GH / GHRH axis — growth-hormone secretagogues (GHRPs, ipamorelin) and GHRH analogs (sermorelin, tesamorelin, CJC-1295).
- Regenerative & repair — BPC-157, TB-500, full-length thymosin beta-4, copper tripeptide GHK-Cu.
- Neuropeptides & nootropics — selank, semax, noopept, dihexa, DSIP, P21, cerebrolysin.
- Khavinson bioregulators — epithalon, cortagen, pinealon, thymalin.
- Immune & antimicrobial — LL-37 cathelicidin, KPV, thymosin alpha-1.
- Reproductive / melanocortin — GnRH analogs, kisspeptin, oxytocin, vasopressin, PT-141, melanotan-2.
- Mitochondrial-derived peptides — humanin, MOTS-c.
Data sources & verification
Where possible, each record cross-references at least two of the following authoritative sources:
- PubChem for canonical SMILES, molecular formula, and computed properties.
- UniProt for endogenous peptides with mapped protein origins (humanin, LL-37, TB-4).
- ChEMBL for receptor-binding and bioactivity data where available.
- CAS Registry for primary substance identifiers.
- PubMed for primary-literature citations linked inline.
Molecular weights are reported as average molecular mass calculated from the canonical sequence unless the entry explicitly states monoisotopic mass. Where peptide complexes (cerebrolysin, thymalin) have no single defined molecular weight, the record indicates this transparently rather than reporting a misleading mean.
Record identifier system
Each monograph is assigned a Peptide Biologix database identifier (BIOLOGIX-YYYY-XXX-NNN) where:
- YYYY — year of first compilation.
- XXX — short alphabetic mnemonic for the compound.
- NNN — record revision number (incremented on substantive content update).
These identifiers are stable; if you cite a record, include the BIOLOGIX-ID to preserve traceability across revisions.
Update cadence
Records are reviewed and revised quarterly. Major revisions are triggered when new clinical data, structural elucidations, or regulatory actions materially change the canonical entry. Minor copy edits and typo fixes do not trigger record renumbering. The complete revision log is maintained internally and available on request.
All data presented in this database is intended for laboratory research, chemistry education, and analytical method development. Many compounds described here are investigational and not approved for human therapeutic use. Researchers must follow all institutional safety, IRB/IACUC, and regulatory requirements applicable to their jurisdiction.
What this database is not
- It is not a vendor catalog. No products are offered for sale on this site.
- It is not medical advice. Compounds described are research tools.
- It is not a clinical guideline. Dosing ranges in monographs are reported from peer-reviewed protocols for reference only.
- It is not affiliated with any commercial peptide supplier, contract manufacturer, or pharmaceutical company.
Errata and corrections
Errors in this database should be reported to the editorial address listed on the contact page. Please include the database record ID, the specific data point in question, and a verifiable citation (PubMed ID, DOI, CAS registry entry). Corrections are reviewed within 72 hours.
Last full review: 2025-05